Tomocube HT-X1 utilizes a low-coherence LED light source to achieve speckle-free, high-contrast imaging without complicated alignments or calibration steps. This enables 3D imaging of thick samples, such as organoids.
A Digital Micro-mirror Device (DMD) is programmed to optimize the illumination patterns to encode specific spatial features of the specimen, providing high-content, high-resolution 3D imaging at exceptional stability.

Holotomography visualizes biological samples label-free based on their intrinsic RI properties, eliminating the need for long exposure to light. This minimizes phototoxicity and optimizes capture speed for 3D imaging to only 6.5 seconds per frame.
Moreover, an integrated stage-stop incubator allows stable environmental control for long-term timelapse observation and monitoring of cellular dynamics.

Especially designed to maximize user flexibility, the HT-X1 employs a unique adaptive illumination module that is tailored for multi-well plates. The combination of high NA, long working distance condenser, DMD, and a motorized illumination unit delivers an efficient illumination pattern for a diverse range of vessel types, from 35-mm dish to 96-well plate and even microfluidic chip.
With the HT-X1, researchers will have more freedom to design their experiments on different sample types using any imaging vessel of their choice.

TomoStudioX works in concert with the HT-X1 platform to visualize and analyze RI tomograms. This intuitive, easy-to-use software empowers users with complete system control, allowing them to handle even the most complex experiments through simple mouse clicks.